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INTERBONE - the interplay among bone cells, matrices and systems

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The skeleton does more than provide just a physical structure to the body. Bone cells play an important role in metabolism, in regulating health and protecting against disease. There is a highly complex web of interactions between bone cells, the other components of skeletal tissue, and cells and organs in other parts of the body. This still poorly understood.

INTERBONE is an international network of scientists investigating this interplay between bone cells and other cells of the body, in relation to three areas of medicine:

  • Energy metabolism
  • Development of bone marrow disease (i.e.leukemia)
  • Fracture healing, tissue regeneration and improved orthopedic implants using biocompatible materials

The research will make use of advanced in vitro cell culture and mouse models to study the role of specific biological molecules in these interactions. For more detailed information on the scientific approach, please view the Project description.

INTERBONE is coordinating research activities between 5 partners in Italy (University of L’Aquila), Netherlands (Erasmus Medical Centre), Brazil (Universidade do Gran Rio), India (Anna University Chennai), and USA (Columbia University).

The main component of the project is a programme of staff exchanges. This involves 20 young scientists (Marie Curie fellows) who will each spend several months working at other laboratories in the network to conduct experiments and learn new scientific techniques. The programme also includes annual symposiums, a workshop and webinars.

The INTERBONE network aims to build new, lasting collaboration in this new area of research, between Europe and global partner nations.

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Consortium members should create an account and request an upgrade from the coordinator to access the private area.

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